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Year : 2017  |  Volume : 4  |  Issue : 4  |  Page : 330-335

Measuring oral mucositis of pediatric patients with cancer: A psychometric evaluation of chinese version of the oral mucositis daily questionnaire

1 Alice Lee Centre for Nursing Studies, National University of Singapore, Singapore
2 School of Nursing, Hong Kong Sanatorium and Hospital, Hong Kong, China
3 Children Cancer Centre, Prince of Wales Hospital, Hong Kong, China
4 Department of Paediatrics and Adolescent Medicine, Tuen Mun Hospital, Hong Kong, China
5 Department of Paediatrics, Queen Elizabeth Hospital, Hong Kong, China
6 Division of Otolaryngology and Head and Neck Surgery, City of Hope, CA, USA

Correspondence Address:
Karis Kin Fong Cheng
Alice Lee Centre for Nursing Studies, Level 2, Clinical Research Centre, National University of Singapore
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/apjon.apjon_39_17

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Objective: Oral mucositis is a frequent clinical condition that has been shown to affect pediatric cancer patients. Oral Mucositis Daily Questionnaire (OMDQ) is one of the few available patient-reported outcome measures to assess the extent and impact of oral mucositis. The objectives of the study were to translate the Mouth and Throat Soreness-Related Questions of the OMDQ into Chinese (OMDQ MTS-Ch) for children and adolescents aged 6–18 years receiving chemotherapy and to evaluate its psychometric properties. Methods: This was part of a multicenter, prospective cohort study involving two phases. Phase I involved forward-backward translation to fit the cognitive and linguistic age level of the children and adolescents, followed by face and content validation, together with pretesting. In Phase II, which evaluated the internal consistency, test-retest reliability, and discriminant validity, a total of 140 patients completed the OMDQ MTS-Ch for 14 days. Results: The OMDQ MTS-Ch had satisfactory face and content validities. The Cronbach's alpha coefficient of the OMDQ MTS-Ch was 0.984. All of the corrected item-total correlations were higher than 0.90. The test-retest intraclass correlation coefficient between consecutive days for the OMDQ MTS-Ch items ranged from 0.576 to 0.983; the only value that was not over 0.70 was that for the paired study days 7 and 8 for the item of talking. The mean area-under-the-curve OMDQ MTS-Ch item scores were significantly different among patients with different degrees of mucositis severity (P < 0.001), supporting the discriminant validity. Conclusions: It has been shown that the OMDQ MTS-Ch has a good level of reliability and discriminant validity and can be completed by children aged ≥6 years and adolescents on a daily basis to measure mucositis and its related functional limitations.

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